The Health Benefits of Lion's Mane

Lion's mane (Hericium erinaceus) is a type of medicinal mushroom. Long used in traditional Chinese medicine, lion's mane is widely available in fresh, dried, and supplement form. Scientific research shows that lion's mane contains a number of health-promoting substances, including antioxidants and beta-glucan. 

Proponents claim that lion's mane mushroom can help with a variety of health problems, including:

• Alzheimer's disease
• Anxiety
• Depression
• High cholesterol
• Inflammation
• Parkison's disease
• Ulcers

In addition, lion's mane is said to strengthen the immune system, stimulate digestion, and protect against cancer.

So far, research on the specific health effects of lion's mane is limited. It is also important to note that the existing findings are primarily from animal-based research, test-tube studies, and small clinical trials. More research is needed before recommending lion's mane as a treatment for any condition.

The research indicates that lion's mane may offer certain health benefits, including support for neuronal health.   Here's a look at some key study findings: 

Lion's mane may benefit adults with mild cognitive impairment, according to a small study published in Phytotherapy Research in 2009. For the study, researchers assigned 30 adults with mild cognitive impairment to take either lion's mane extract or a placebo every day for 16 weeks. In cognitive tests given at weeks eight, 12, and 16 of the study, members of the lion's mane group showed significantly greater improvements compared to members of the placebo group.

In a more recent study (published in Biomedical Research in 2011), scientists examined the effects of lion's mane on brain function in mice. Results revealed that lion's mane helped protect against memory problems caused by the buildup of amyloid beta (a substance that forms the brain plaques associated with Alzheimer's disease.

Studies have also shown a possible neuroprotective effect against ischemic stroke.

Research to date suggests that lion's mane may help alleviate depression and anxiety. For example, a 2020 review of the literature called lion's mane "a potential alternative medicine for the treatment of depression."

Likewise, a 2021 research review detailed several studies that showed significant anti-anxiety effects. Lion's mane appears to offer "neuroprotective functions, cytotoxicity, anticarcinogenic, antidiabetic, antimicrobial, and herbicidal activities," as well.

Little is known about the safety of long-term use and side effects of lion's mane supplements.  However, there's some concern that lion's mane may aggravate symptoms in people with allergies and asthma. Therefore, it's important to consult your physician prior to using lion's mane or any other supplement, especially if you have a history of allergies, asthma, and/or any other medical condition. 

Lion's mane hasn't been studied enough to establish standard dosages and preparation.  General guidelines follow, but always heed your physician's specific advice regarding medicines and supplements.

Lion's mane is commonly consumed in many Asian countries for medicinal and culinary purposes, but there are no consistent formulations or dosage recommendations. Follow the instructions on your package of lion's mane closely.